Author Brockmöller, Jürgen
-
2002 | Journal Article
Validity of PCR with emphasis on variable number of tandem repeat analysis
Kaiser, R.; Tremblay, P.-B.; Roots, I. & Brockmöller, J. (2002)
Clinical Biochemistry, 35(1) art. PII S0009-9120(02)00273-4. DOI: https://doi.org/10.1016/S0009-9120(02)00273-4
Details DOI PMID PMC WoS
-
2007 | Journal Article
Genetic polymorphisms in the amino acid transporters LAT1 and LAT2 in relation to the pharmacokinetics and side effects of melphalan
Kühne, A.; Kaiser, R.; Schirmer, M.; Heider, U.; Muhlke, S.; Niere, W. & Overbeck, T. et al. (2007)
Pharmacogenetics and Genomics, 17(7) pp. 505-517. DOI: https://doi.org/10.1097/FPC.0b013e3280ea77cd
Details DOI PMID PMC WoS
-
2010 | Journal Article |
CYP2D6 and CYP2C19 in Papua New Guinea: High frequency of previously uncharacterized CYP2D6 alleles and heterozygote excess.
von Ahsen, N.; Tzvetkov, M.; Karunajeewa, H. A.; Gomorrai, S.; Ura, A.; Brockmöller, J. & Davis, T. M. E. et al. (2010)
International journal of molecular epidemiology and genetics, 1(4) pp. 310-9.
Details PMID PMC
-
2020 | Journal Article
Differences in Metformin and Thiamine Uptake between Human and Mouse Organic Cation Transporter 1: Structural Determinants and Potential Consequences for Intrahepatic Concentrations
Meyer, M. J.; Tuerkova, A.; Römer, S.; Wenzel, C.; Seitz, T.; Gaedcke, J. & Oswald, S. et al. (2020)
Drug Metabolism and Disposition, 48(12) pp. 1380-1392. DOI: https://doi.org/10.1124/dmd.120.000170
Details DOI
-
2021 | Journal Article
How do psychostimulants enter the human brain? Analysis of the role of the proton-organic cation antiporter
Sachkova, A.; Doetsch, D. A.; Jensen, O.; Brockmöller, J. & Ansari, S. (2021)
Biochemical Pharmacology, art. S0006295221003671. DOI: https://doi.org/10.1016/j.bcp.2021.114751
Details DOI
-
2021 | Journal Article
The roles of caffeine and corticosteroids in modulating cortical excitability after paired associative stimulation (PAS) and transcranial alternating current stimulation (tACS) in caffeine-naïve and caffeine-adapted subjects
Zulkifly, M. F. M.; Merkohitaj, O.; Paulus, W. & Brockmöller, J. (2021)
Psychoneuroendocrinology, 127 pp. 105201. DOI: https://doi.org/10.1016/j.psyneuen.2021.105201
Details DOI
-
2021 | Journal Article | Research Paper |
Isobutyrylcarnitine as a Biomarker of OCT1 Activity and Interspecies Differences in its Membrane Transport
Jensen, O.; Matthaei, J.; Klemp, H. G.; Meyer, M. J.; Brockmöller, J. & Tzvetkov, M. V. (2021)
Frontiers in Pharmacology, 12. DOI: https://doi.org/10.3389/fphar.2021.674559
Details DOI
-
2021 | Journal Article |
8-Oxoguanine DNA Glycosylase (OGG1) Cys326 Variant: Increased Risk for Worse Outcome of Patients with Locally Advanced Rectal Cancer after Multimodal Therapy
Leu, M.; Riebeling, T.; Dröge, L. H.; Hubert, L.; Guhlich, M.; Wolff, H. A. & Brockmöller, J. et al. (2021)
Cancers, 13(11) pp. 2805. DOI: https://doi.org/10.3390/cancers13112805
Details DOI
-
2021 | Journal Article |
CYP2B6 Functional Variability in Drug Metabolism and Exposure Across Populations—Implication for Drug Safety, Dosing, and Individualized Therapy
Langmia, I. M.; Just, K. S.; Yamoune, S.; Brockmöller, J.; Masimirembwa, C. & Stingl, J. C. (2021)
Frontiers in Genetics, 12. DOI: https://doi.org/10.3389/fgene.2021.692234
Details DOI
-
2021 | Journal Article | Research Paper |
Overlap and Specificity in the Substrate Spectra of Human Monoamine Transporters and Organic Cation Transporters 1, 2, and 3
Gebauer, L.; Jensen, O.; Neif, M.; Brockmöller, J. & Dücker, C. (2021)
International Journal of Molecular Sciences, 22(23) art. 12816. DOI: https://doi.org/10.3390/ijms222312816
Details DOI
-
2021 | Journal Article | Research Paper |
Effects of Genetic Polymorphism in CYP2D6, CYP2C19, and the Organic Cation Transporter OCT1 on Amitriptyline Pharmacokinetics in Healthy Volunteers and Depressive Disorder Patients
Steimer, W.; Pischa, K.; Leucht, S.; Kullmann, M.; Ouethy, T.; Rafehi, M. & Matthaei, J. et al. (2021)
Frontiers in Pharmacology, 12. DOI: https://doi.org/10.3389/fphar.2021.688950
Details DOI
-
2021 | Journal Article
Confounding effects of caffeine on neuroplasticity induced by transcranial alternating current stimulation and paired associative stimulation
Zulkifly, M. F. M.; Merkohitaj, O.; Brockmöller, J. & Paulus, W. (2021)
Clinical Neurophysiology, 132(6) pp. 1367-1379. DOI: https://doi.org/10.1016/j.clinph.2021.01.024
Details DOI
-
2022 | Journal Article
Amino acids in transmembrane helix 1 confer major functional differences between human and mouse orthologs of the polyspecific membrane transporter OCT1
Meyer, M. J.; Schreier, P. C.; Basaran, M.; Vlasova, S.; Seitz, T.; Brockmöller, J. & Zdrazil, B. et al. (2022)
Journal of Biological Chemistry, art. S0021925822004148. DOI: https://doi.org/10.1016/j.jbc.2022.101974
Details DOI
-
2022 | Journal Article
Molecular basis for stereoselective transport of fenoterol by the organic cation transporters 1 and 2
Gebauer, L.; Arul Murugan, N.; Jensen, O.; Brockmöller, J. & Rafehi, M. (2022)
Biochemical Pharmacology, 197 art. S0006295221004974. DOI: https://doi.org/10.1016/j.bcp.2021.114871
Details DOI
-
2022 | Journal Article |
Stereoselectivity in the Membrane Transport of Phenylethylamine Derivatives by Human Monoamine Transporters and Organic Cation Transporters 1, 2, and 3
Gebauer, L.; Rafehi, M. & Brockmöller, J. (2022)
Biomolecules, 12(10) pp. 1507. DOI: https://doi.org/10.3390/biom12101507
Details DOI
-
2022 | Journal Article |
Atypical Substrates of the Organic Cation Transporter 1
Redeker, K. Redeker, Kyra-Elisa Maria; Jensen, O.; Gebauer, L.; Meyer-Tönnies, M. J. & Brockmöller, J. (2022)
Biomolecules, 12(11) pp. 1664. DOI: https://doi.org/10.3390/biom12111664
Details DOI
-
2023 | Journal Article |
Combined and independent effects of OCT1 and CYP2D6 on the cellular disposition of drugs
Gebauer, L.; Dücker, C.; Jensen, O. & Brockmöller, J. (2023)
Biomedicine & Pharmacotherapy, 161 art. 114454. DOI: https://doi.org/10.1016/j.biopha.2023.114454
Details DOI
-
2023 | Journal Article
Stereoselective Inhibition of High- and Low-Affinity Organic Cation Transporters
Gebauer, L.; Jensen, O.; Rafehi, M. & Brockmöller, J. (2023)
Molecular Pharmaceutics, art. acs.molpharmaceut.3c00691. DOI: https://doi.org/10.1021/acs.molpharmaceut.3c00691
Details DOI
-
2023 | Journal Article
Stereoselectivity in Cell Uptake by SLC22 Organic Cation Transporters 1, 2, and 3
Gebauer, L.; Jensen, O.; Rafehi, M. & Brockmöller, J. (2023)
Journal of Medicinal Chemistry, 66(23) pp. 15990-16001. DOI: https://doi.org/10.1021/acs.jmedchem.3c01436
Details DOI
-
2023 | Journal Article |
Oral Drug Absorption and Drug Disposition in Critically Ill Cardiac Patients
Harnisch, L.-O. ; Brockmöller, J.; Hapke, A.; Sindern, J.; Bruns, E.; Evertz, R. & Toischer, K. et al. (2023)
Pharmaceutics, 15(11) pp. 2598. DOI: https://doi.org/10.3390/pharmaceutics15112598
Details DOI